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西军136(即羟基奎呱)是4~氨基奎啉类化合物,系西安制药厂和第二军医大学协作研制的一种新抗疟药。1975年在安徽、浙江两地和海南抗性疟区分别对一些间日疟病例和抗氯奎恶性疟病例进行了观察,初步认为西军136的临床疗效尚好,值得扩大试用。我组受第二军医大学的委托,于1976年6~10月在乐东、崖县的抗性疟区内用西军136合并伯奎治疗恶性疟15例,并用等剂量奎呱合并伯奎作对照,现将观察情况小结如下:
West Army 136 (Hydroxyquinoguan) is a 4-amino-quinoline compounds, the Department of Xi’an Pharmaceutical Factory and the Second Military Medical University developed a new antimalarial drug. In 1975 in Anhui, Zhejiang and Hainan resistant malaria areas were some cases of vivax malaria and chloroquine resistant malaria cases were observed, initially that the clinical efficacy of the West Army 136 is still good, it is worth expanding trial. My group was commissioned by the Second Military Medical University, from June to October 1976 in Ledong, Yaxian resistance malaria area with the West Army 136 combined with beikacin treatment of 15 cases of falciparum malaria, For comparison, the observation is summarized as follows: