药物引起的谵妄是较常见的药源性疾病,尤其是存在易感因素(如高龄、神经系统疾病、外科手术和危重症等)的患者更为常见。药源性谵妄主要与药物影响神经递质的合成、释放和代谢,导致神经功能紊乱有关。引起谵妄的药物主要为抗胆碱药和抗抑郁药。合理用药可避免药源性谵妄的发生,及早辨识谵妄症状并及时处理尤为重要。 Drug-induced delirium is the most common drug-borne disease, especially in patients with predisposing factors such as advanced age, neurological diseases, surgery, and critically ill patients. Drug-induced delirium and drugs mainly affect the neurotransmitter synthesis, release and metabolism, leading to neurological disorders. Drugs that cause delirium are mainly anticholinergics and antidepressants. Rational medication can avoid the occurrence of drug-induced delirium, early identification of delirium symptoms and timely treatment is particularly important.