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目的运用彩色多普勒超声序贯监测妊娠早、中和晚期子宫动脉血流特征并制定各个孕期相应的参考值。方法2005-04-2006-04随机对南京医科大学第一附属医院妇产科160例妊娠妇女通过彩色多普勒超声在孕10~14周、20~24周、30~34周以及50例非妊娠期妇女序贯监测子宫动脉血流动力学3项参数S/D(收缩期峰值流速/舒张末期流速)、PI(搏动指数)和RI(阻力指数)。结果(1)妊娠期血流动力学3项参数与非妊娠期相比显著性降低(P<0·01),并随孕周增加逐渐降低,不同孕期之间差异均有显著性(P<0·01)。(2)不同孕周的3项参数均为正态分布。其参考值范围(双侧95%的界限值)分别为:早孕期:RI(0·73±0·16)、PI(1·66±0·86)、S/D(4·12±2·69);中孕期RI(0·56±0·16)、PI(0·94±0·47)、S/D(2·36±1·06);晚孕期RI(0·51±0·18)、PI(0·82±0·45)、S/D(2·13±1·02)。结论随着妊娠进展,子宫动脉血流动力学3项参数逐渐降低。深入讨论这些参数的参考值范围有助于准确、全面地评估妊娠状态和预测妊娠结局。
Objective To monitor the characteristics of uterine artery blood flow in early, middle and late stages of pregnancy by color Doppler echocardiography, and to develop the corresponding reference values in each pregnancy. Methods From April 2005 to April 2006, 160 pregnant women in the obstetrics and gynecology department of the First Affiliated Hospital of Nanjing Medical University were randomly divided into three groups: pregnant women of 10-14 weeks, 20-24 weeks, 30-34 weeks of pregnancy and 50 cases of non-pregnant women by color Doppler ultrasonography The gestational women monitored sequentially 3 parameters of uterine artery hemodynamics: S / D (peak systolic flow / end diastolic flow), PI (pulsatility index) and RI (resistance index). Results (1) The three parameters of hemodynamics in pregnancy were significantly lower than those in non-pregnancy (P <0.01), and gradually decreased with the increase of gestational age. There were significant differences in different pregnancy stages (P < 0 · 01). (2) The three parameters of different gestational weeks are normal distribution. The reference value range (95% thresholds on both sides) was as follows: early pregnancy: RI (0.73 ± 0.16), PI (1.66 ± 0.86), S / D · RI (0 · 56 ± 0 · 16), PI (0 · 94 ± 0 · 47), S / D (2 · 36 ± 1 · 06) · 18), PI (0 · 82 ± 0 · 45), S / D (2 · 13 ± 1 · 02). Conclusion With the progress of pregnancy, the three parameters of uterine artery hemodynamics gradually decreased. An in-depth discussion of the reference values for these parameters helps to accurately and comprehensively assess pregnancy status and predict pregnancy outcomes.