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目的:探讨桂林西瓜霜对宫颈糜烂VEGF mRNA的表达。方法:将160例宫颈糜烂患者随机分治疗组(用桂林西瓜霜喷敷)、对照组(用bFGF-胶原蛋白海绵贴敷)。应用RT-PCR检测两组宫颈糜烂组织治疗前、后VEGF mRNA的表达。结果:治疗前组织中VEGF mRNA表达两组相对量分别0.48±0.14、0.51±0.11,组间差异无统计学意义(P>0.05);治疗后两组表达均显著增加,相对表达量分别0.79±0.13、0.75±0.16,两组治疗后表达量与治疗前比较差异有统计学意义(P<0.01),组间差异无统计学意义(P>0.05)。结论:桂林西瓜霜对宫颈糜烂上皮组织VEGF mRNA表达有增强作用。
Objective: To investigate the expression of VEGF mRNA in Guilin watermelon cream on cervical erosion. Methods: 160 patients with cervical erosion were randomly divided into treatment group (watermelon frost spray Guilin), control group (with bFGF-collagen sponge stick). RT-PCR was used to detect the expression of VEGF mRNA in cervical erosion group before and after treatment. Results: The relative amounts of VEGF mRNA in the two groups before treatment were 0.48 ± 0.14 and 0.51 ± 0.11, respectively. There was no significant difference between the two groups (P> 0.05). After treatment, the expression of VEGF mRNA in both groups increased significantly 0.13,0.75 ± 0.16, the difference between the two groups after treatment was statistically significant (P <0.01). There was no significant difference between the two groups (P> 0.05). Conclusion: Guilin watermelon cream can enhance the expression of VEGF mRNA in cervical erosion epithelial tissue.