十二指肠溃疡(DU)和幽门螺旋菌(HP)密切相关。许多研究表明HP的根除可减少DU的复发。以往此类研究多为2年或更短的随访研究。本研究随访了一组最早参加HP根除治疗(HET)对照研究的DU患者,以观察HET的远期疗效。 病人和方法:100例曾参加1985～1986年HET双盲对照研究的患者,均有胃镜临床资料和HP感染的原始记录和随访记录。由一名对患者过去病史不了解的胃肠病专家进行胃镜复 Duodenal ulcer (DU) and Helicobacter pylori (HP) are closely related. Many studies have shown that the eradication of HP can reduce the recurrence of DU. In the past, most of these studies were 2 years or less follow-up study. This study followed a group of DU patients who were the earliest participants in the HP eradication therapy (HET) control study to observe the long-term efficacy of HET. Patients and Methods: A total of 100 patients who had participated in the double-blind study of HET between 1985 and 1986 were enrolled in both primary and follow-up records of gastroscopic clinical data and HP infection. Gastroscopy was performed by a gastroenterologist who did not know the patient’s past medical history