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Combined IV and intra- arterial (IA) thrombolysis for acute ischemic stroke may offer advantages over either technique alone. Sixty- two non- randomized patients with NIH Stroke Scale scores of ≥ 10 who met standard criteria for IV thrombolysis were treated with an IV/IA approach. Three- month modified Rankin Scale scores were 0 to 2 for 50% of patients, mortality was 18% , and symptomatic intracerebral hemorrhage occurred in 8% . IV/IA thrombolysis appeared safe and effective in this group.
Combined IV and intra-arterial (IA) thrombolysis for acute ischemic stroke may offer advantages over either technique alone. Sixty-two non- randomized patients with NIH Stroke Scale scores of ≥ 10 who with standard criteria for IV thrombolysis were treated with an IV / IA approach. Three-month modified Rankin Scale scores were 0 to 2 for 50% of patients, mortality was 18%, and symptomatic intracerebral hemorrhage occurred in 8%. IV / IA thrombolysis was safe and effective in this group.