Evaluation of Coronary Artery Disease Using Technetium-99m-Sestamibi First-Pass and Perfusion Imagin

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The aims of this study were: (1) to test whether first-pass radio-nuclide angiocardiography (FPRNA) adds userul information to perfusion scintigraphy; and (2) to assess the relative accuracy of perfusion and functional imaging in combination with dipyndam ole for the evaluation of CAD. Methods: Thirty patients with angiographically proven CAD (17 with prior infaction) were studied on separate days at rest and with dipyridamole infusion (0.7rog/kg over 4 min). Tomographic images were evaluated using an uptake score. Dipyridamole FPRNA was considered positive in case of stress-induced wall motion abnormality or ejection fracticn decrease. Results: The CAD detection rate of perfusion imaging was 100%, while that of FPRNA was 70% using wall marion criteria, 63% using ejection fraction response and 77% condidering any abnormality. 96% specificity and 82% accuracy. FPRNA results were 50%, 100% and 80% respectively. Perfusion imaging was significantly The aims of this study were: (1) to test whether first-pass radio-nuclide angiocardiography (FPRNA) adds userul information to perfusion scintigraphy; and (2) to assess the relative accuracy of perfusion and functional imaging in combination with dipyndam ole for the evaluation of CAD. Methods: Thirty patients with angiographically proven CAD (17 with prior infaction) were studied on separate days at rest and with dipyridamole infusion (0.7 gr / kg over 4 min.) Tomographic images were evaluated using an uptake score. Results: The CAD detection rate of perfusion imaging was 100% while that of FPRNA was 70% using wall marion criteria, 63% using fraction fraction response and 77% condidering any abnormality. 96% specificity and 82% accuracy. FPRNA results were 50%, 100% and 80% respectively. Perfusion imaging was significantly
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