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血栓闭塞性脉管炎(Thromboangiitis Obliterans,TAO)在我国的发病率较高。其病因不清,机理复杂。吸烟在TAO发生和发展中起着重要作用,这一点,已被绝大多数学者所公认。其它诸如营养不良、寒潮刺激、细菌感染和外伤等,也被认为是此病发生的因素。 近20年来,免疫因素在TAO发病机理中的作用日渐受到重视,不少学者的研究结果都提示TAO可能为自身免疫性疾病,因而就TAO免疫学研究资料进行综述。
Thromboangiitis obliterans (TAO) in our country a higher incidence. Its etiology is unclear, the mechanism is complicated. Smoking has played an important role in the occurrence and development of TAO, which has been recognized by most scholars. Other factors such as malnutrition, cold stimulation, bacterial infections and trauma are also considered factors. In recent 20 years, the role of immune factors in the pathogenesis of TAO has attracted more and more attention. The results of many scholars suggest that TAO may be an autoimmune disease. Therefore, the literature about TAO immunology is reviewed.