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(continued)4Effectsofbipkospkonatesforbonemetastasesofpatientswithgynecologiccancer[8,10,11]4.1ABiphosphonatesTheywerepyrophosphateanaloguesinwhichtheoxygenbridgehadbeenreplacedbyacarbon(P-C-P)withvarioussidechains.Theytightlyboundtocalcifiedbonematrix,hy
(continued) 4 Effects of biphospkonates for bone metastases of patients with cytotoxic cancer [