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目的 :分析影响法洛四联症患者存活的因素。方法 :对 2 134例法洛四联症患者的资料进行回顾性分析。根据住院时年龄分儿童组和成人组 ,成人组 (≥ 15岁 ) 4 6 0例 ,儿童组 (<15岁 ) 16 74例。通过症状、体征、X线胸片、心电图、超声心动图和心血管造影资料分析 ,观察其临床表现特点。结果 :经统计学处理发现低氧发作、右室流出道狭窄的严重程度、左心室发育不良和并存的其它心脏畸形的发生率 ,儿童组显著高于成人组 (P<0 .0 1) ,而肺动脉瓣下室缺的发生率 ,成人组则显著高于儿童组 (P<0 .0 1)。结论 :低氧发作 ,右室流出道狭窄的范围及程度 ,室缺位置 ,左室大小和并存畸形是影响法洛四联症患者存活的主要因素。
Objective: To analyze the factors influencing the survival of patients with tetralogy of Fallot. Methods: The data of 2 134 patients with tetralogy of Fallot were retrospectively analyzed. According to the age group of children in the hospital, there were 460 cases in the adult group (≥15 years old) and 1674 cases in the children group (<15 years old). Through the symptoms, signs, chest X-ray, electrocardiogram, echocardiography and cardiovascular angiography data analysis, to observe the clinical features. Results: The incidence of hypoxemia, severity of right ventricular outflow tract stenosis, left ventricular dysplasia and other cardiac malformations were significantly higher in children than in adults (P <0.01) after statistical analysis. The incidence of pulmonary inferior ventricular septal defect was significantly higher in adults than in children (P <0.01). CONCLUSION: The main factors affecting the survival of patients with tetralogy of Fallot due to hypoxemia, the extent and extent of right ventricular outflow tract stenosis, ventricular septal defect, left ventricular size and congenital malformations.