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目的：分析9例何杰金淋巴瘤（HD）较罕见的皂泡状骨病变之X线表现及其形成机制，提高对有类似表现的骨肿瘤鉴别诊断的认识。材料与方法：1959～1995年间有32例HD骨受侵病例。9例表现为皂泡状骨病变（28．12％），男8例，女1例。年龄14～65岁。病理亚型为结节硬化型5例，混合细胞型3例，淋巴细胞为主型1例。单发病变8例，多发1例。由确诊HD至发现骨病变间隔时间为0～77个月。9例均有X线片，结果：胸骨3例，髂骨3例，肋骨2例，桡骨1例。病变最大径4～10cm，边缘清楚，9例病变内部见粗／细的小梁分隔，4例可见硬化边，5例有局部软组织肿物，1例见花边状骨膜反应。治疗后可见肿物缩小，硬化边更清楚或增厚，内部骨性分隔增多或增粗。结论：HD形成皂泡状骨病变与病理亚型有一定关系；HD应列入皂泡状骨病变的鉴别诊断。
OBJECTIVE: To analyze the X-ray findings and the formation mechanism of 9 rare cases of Hodgkin’s lymphoma (HD) and to improve the understanding of the differential diagnosis of bone tumors with similar manifestations. Materials and Methods: There were 32 cases of bone involvement in HD from 1959 to 1995. Nine cases showed bacteriological lesions (28.12%), 8 males and 1 female. Age 14 to 65 years old. Pathological subtypes were 5 cases of nodular sclerosis, 3 cases of mixed cell type, and 1 case of lymphocyte type. Single lesions in 8 cases, multiple cases. From diagnosis of HD to the discovery of bone lesions between 0 and 77 months. All the 9 cases had X-ray films. The results were: 3 cases of sternum, 3 cases of zygomatic bone, 2 cases of ribs, and 1 case of zygomatic bone. The maximum diameter of the lesion was 4 to 10 cm, and the edge was clear. In 9 lesions, the trabecula was divided into thick/thin trabeculae. Four patients had sclerotic edges. Five patients had local soft-tissue masses and one patient had lace-like periosteal reactions. After treatment, the tumor was reduced, the sclerotic edge was clearer or thicker, and the internal osseous separation was increased or thickened. Conclusion: There is a certain relationship between the formation of SOB lesions in HD and pathological subtypes; HD should be included in the differential diagnosis of SOB lesions.