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中药配伍中相反指两种药物合用产生或增强毒性或使疗效降低,而“十八反”是重要的配伍禁忌,也是现代药性理论争议最多的问题,且至今尚未形成较统一的判断标准和结论。主要介绍了“十八反”中有关海藻、芫花反甘草的毒性和机制研究,探讨了影响“十八反”的因素,并在此基础上提出根据不同药物的特点确定其特定部位的安全药理实验内容的观点。
On the contrary, the compatibility of traditional Chinese medicine refers to the combination of two drugs to produce or enhance toxicity or reduce efficacy, and “anti-18” is an important compatibility taboo, but also the most controversial issues of modern medicine theory, and has not yet formed a more uniform standard of judgment And conclusion. This paper mainly introduces the research on the toxicity and mechanism of seaweed and Daphne genkwa against licorice in “Eighteen Antibodies”, and discusses the factors that influence the “Eighteen Antibodies”. On the basis of this, it is proposed that according to the characteristics of different drugs, Specific site of the safety of pharmacological experiments content point of view.