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利用血友病人中发生的病毒性肝炎的急性期和恢复期血清,建立了一种固相放射免疫方法,用于检出一种经血液传播的非甲非乙(NANB)肝炎。与其它急性病毒性肝炎和慢性肝病作对照,表明这一检测系统的特异性良好。在临床诊断的急性和慢性NANB肝炎中,单份血清NANB的检出率分别为40.0％和34.4％,如检测病程中的一系列血清,NANB·Ag及(或)NANB·Ab的合并检出率分别可达96.0％和68.8％。在急性期出现NANB·Ag的10例病人中,有6例在抗
Acute phase and convalescent serum of viral hepatitis occurred in hemophilia patients was used to establish a solid-phase radioimmunoassay to detect a blood-borne non-A non-B hepatitis (NANB). In contrast to other acute viral hepatitis and chronic liver disease, the specificity of this test system is good. Among the clinically diagnosed cases of acute and chronic NANB hepatitis, the detection rates of single serum NANB were 40.0% and 34.4%, respectively. For example, a series of serums were detected during the course of the disease, and the combined detection of NANB Ag and / or NANB Ab Rates up to 96.0% and 68.8% respectively. Of the 10 patients with NANB Ag present in the acute phase, 6 were resistant