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自从Pearse1968年在研究甲状腺内分泌细胞后,提出含胺和/或摄取胺前体并脱羧反应细胞(amine content and/or amine precursor uptake and decar boxylation cell.APUD细胞)系统以来,随着内分泌细胞研究的迅速发展,胃肠胰内分泌细胞系统(Gas troentero-pankreatisches System,GEP System)也被认为是Pearse’s APUD系统的成员。目前,APUD细胞归纳于神经内分泌细胞,因其含有多肽成分(现称调节性多肽,regulatory peptides),并发生于神经系。Dayal认为分布于中枢神经系统之外的神经内分泌细胞都称为APUD细胞,共同组成一个分散的
Since Pearse researched thyroid endocrine cells in 1968, it has proposed the system of amine content and/or amine precursor uptake and decar boxylation cell (APUD), with the study of endocrine cells. The rapid development of Gastroentero-pankreatisches System (GEP System) is also considered as a member of Pearse’s APUD system. At present, APUD cells are classified into neuroendocrine cells because they contain polypeptide components (now referred to as regulatory peptides) and occur in the nervous system. Dayal believes that neuroendocrine cells that are distributed outside the central nervous system are called APUD cells, which together form a dispersed