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目的探讨环孢素联合雄激素及复方皂矾丸治疗再生障碍性贫血的疗效。方法治疗组服用环孢素100mg,2次/d,同时加用雄激素及复方皂矾丸;对照组应用雄激素及复方皂矾丸,用量及方法同治疗组,但不服用环孢素。结果治疗组59例,基本治愈2例,缓解25例,明显进步27例,无效5例,总有效率91.53%;对照组53例,基本治愈1例,缓解12例,明显进步21例,无效19例,总有效率64.15%。两组比较差异有统计学意义(P<0.05)。结论环孢素联合雄激素及复方皂矾丸治疗再生障碍性贫血疗效较好,未增加明显不良反应。
Objective To investigate the curative effect of cyclosporine combined with androgen and compound Zaofan pill in the treatment of aplastic anemia. Methods The treatment group taking cyclosporine 100mg, 2 times / d, while adding androgen and compound soap vanilloid; control group and the application of androgen compound capsules, the amount and method with the treatment group, but did not take ciclosporin. Results In the treatment group, 59 cases were cured basically, 2 cases basically cured, 25 cases relieved, 27 cases markedly improved, 5 cases ineffective and the total effective rate was 91.53%. In the control group, 53 cases were basically cured, 12 cases were alleviated, 21 cases were markedly improved, 19 cases, the total efficiency of 64.15%. The difference between the two groups was statistically significant (P <0.05). Conclusion Cyclosporine combined with androgen and compound Zaofan pills in the treatment of aplastic anemia better effect, did not increase the apparent adverse reactions.