1临床资料:赵某男,70岁。因两侧小腿及双足红肿、糜烂伴疼痛,后背皮肤粗糙、增厚伴裂隙3年余,加重半年。于2007年4月26日到我院就诊。由于糖尿病20余年,患者周身皮肤瘙痒,反复搔抓,曾多次在外院治疗,症状时而缓解,时而加重。近3年皮疹逐渐增多且增厚。近1年双足红肿、糜烂,在外 1 clinical data: Zhao male, 70 years old. Due to both sides of the legs and feet swelling, erosion with pain, rough skin back, thickening with more than 3 years of fracture, aggravate for six months. On April 26, 2007 to our hospital. As diabetes more than 20 years, patients with skin itchy skin, repeated scratching, has repeatedly treated outside the hospital, symptoms sometimes relieve, occasionally aggravating. Rash gradually increased and thickening in the past 3 years. Nearly 1 years feet swelling, erosion, outside