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频率应答起搏器的主要适应证是有心脏变时功能不全的病窦综合征患者,但合并冠心病心绞痛患者,频率应答中起搏心率的增加,可能诱发或加重心绞痛发作。研究表明起搏心率增加导致心肌需氧的不利作用与在较高起搏频率通过减少左室舒张未压,随之增加心肌血流的潜在益处相抵消。频率应答起搏器不会增加心肌缺血。目前频率应答起搏器有几种感知特性,要根据患者情况,选择合适的感知特性的起搏器。
The main indication of frequency response pacemaker is sick sinus syndrome patients with cardiac dysfunction, but patients with coronary heart disease and angina pectoris, frequency response pacing heart rate increases, may induce or aggravate angina pectoris. Studies have shown that adverse effects of increased cardiac arrhythmia on myocardial oxygen demand are offset by the potential benefits of higher pacing rates by reducing left ventricular diastolic pressure followed by increased myocardial blood flow. Frequency response pacemaker does not increase myocardial ischemia. The current frequency response pacemaker has several perceptive characteristics, according to the patient’s condition, select the appropriate sense of pacemaker.