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为了观察前列腺素E_2对复发性阿弗它溃疡的治疗作用,作者选择35例轻型复发性阿弗它溃疡分为两组进行对比研究。前列腺素E_2(PGE_2)组患者用塑料药匙取含有PGE_2的凝胶涂布于溃疡表面,每次PGE_2用量为0.3 mg,每日2次,疗程10天,溃疡愈合则停止上药。对照组使用不含PGE_2的安慰剂凝胶,用药方法同上。用药后1,3,5,7,10天患者复诊检查。结果共有33人完成此项试验,在18例应用PGE_2治疗的病例,有9例在10天的研究中未再出现新溃疡,而使用安慰剂的
In order to observe the therapeutic effect of prostaglandin E_2 on recurrent aphthous ulcer, the author chose 35 cases of light recurrent aphthous ulcer divided into two groups for comparative study. Patients in prostaglandin E_2 (PGE_2) group were treated with PGE_2-containing gel on the surface of ulcer with a plastic medicine spoon. The dosage of PGE_2 was 0.3 mg twice daily for 10 days and the ulcer healed. The control group received placebo gels without PGE 2 using the same method as above. 1,3,5,7,10 patients after treatment referral examination. A total of 33 patients completed the trial. Of the 18 patients treated with PGE_2, 9 had no new ulcers in the 10-day study compared with placebo