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目的:评价经导管置入Amplatzer封堵器治疗Ⅱ孔型心房间隔缺损(ASD)的疗效。方法:全组20例,术前经胸超声心动图(TTE)检查示ASD存在,所有病例均在透视及经TTE监视下经导管置入Amplatzer封堵器封堵ASD。术后24h,1、3及6个月分别行TTE、心电图及X线胸片检查评价治疗效果。结果:20例ASD患儿封堵器置入均获得成功,术中未发生任何并发症,无急诊手术病例。术后24h,1、3、6个月TTE检查,示心房水平分流消失,未见封堵器对心房壁及二尖瓣、三尖瓣运动产生影响,均未见封堵器移位及ASD再通;X线胸片检查显示术后24h,1、3、6个月肺血较术前均有不同程度减少。术后6个月右心房、室内径均恢复至正常范围。结论:经导管置入Amplatzer封堵器治疗ASD是一种有效的非手术方法,具有操作简便、安全、技术成功率高及封堵效果好等诸多优点,其临床应用的远期疗效尚需继续观察。
Objective: To evaluate the efficacy of transcatheter Amplatzer occluder for the treatment of type Ⅱ atrial septal defect (ASD). Methods: A total of 20 patients with ASD were examined by transthoracic echocardiography (TTE) before operation. All patients underwent transcatheter closure of ASD under fluoroscopy and TTE monitoring. Twenty-four, one, three and six months after surgery were performed TTE, ECG and X-ray examination to evaluate the therapeutic effect. Results: Twenty occluders in children with ASD were successfully treated. There were no complications and no emergency operation in the operation. TTE at 24h, 1, 3, 6 months after operation showed that the atrium level shunt disappeared, and no occluder affected the movement of atrial wall, mitral and tricuspid valves. No occluder displacement and ASD Recanalization; X-ray examination showed that after 24h, 1,3,6 months of lung blood were reduced to varying degrees compared with preoperative. Right atrium and ventricular diameter recovered to the normal range at 6 months after operation. Conclusion: Transcatheter Amplatzer occluder is an effective non-surgical treatment for ASD. It has many advantages such as easy operation, safety, high technical success rate and good occlusion effect. The long-term effect of clinical application should be continued Observed.