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目的评价急性心肌梗死后不同时间段应用Diver CE抽吸导管的疗效。方法急性ST段抬高型心肌梗死(STsegment elevation acute myocardial infarction,STEMI)患者220例,均在冠状动脉造影后行血栓抽吸,植入支架。根据心肌缺血症状发生至抽吸导管使用时间分为观察组(<3h)和对照组(≥3~12h)各110例,观察并比较2组术后心肌梗死溶栓治疗(thrombolysis in myocardial infarction,TIMI)分级、校正TIMI帧数(corrected TIMI frame count,cTFC)、术后2hST段回落率(ST-segment recovery,STR)等再灌注指标。结果 2组年龄,性别比例,合并高血压、2型糖尿病、高脂血症情况、吸烟史和梗死相关血管部位比较差异均无统计学意义(P>0.05);观察组术后即刻TIMI 3级血流比率(88.2%)、STR≥50%比率(82.7%)高于对照组(64.5%、68.1%),cTFC[(25.7±6.1)帧]低于对照组[(40.1±11.2)帧],2组比较差异均有统计学意义(P<0.05)。结论发生急性心肌梗死后3h内应用Diver CE抽吸导管可获更佳疗效。
Objective To evaluate the efficacy of Diver CE aspiration catheter at different time points after acute myocardial infarction. Methods A total of 220 patients with acute ST-segment elevation myocardial infarction (STEMI) underwent thrombus aspiration and stent implantation after coronary angiography. According to the occurrence of myocardial ischemia to suction catheter using time divided into the observation group (<3h) and the control group (≥ 3 ~ 12h) in 110 cases, observed and compared two groups after myocardial infarction thrombolysis (thrombolysis in myocardial infarction , TIMI), corrected TIMI frame count (cTFC), post-2h ST-segment recovery (STR) and other indicators of reperfusion. Results There were no significant differences in age, sex ratio, hypertension, type 2 diabetes, hyperlipidemia, smoking history and infarct-related vascular sites between the two groups (P> 0.05) The blood flow rate (88.2%), STR≥50% (82.7%) was higher than that of the control group (64.5%, 68.1%), while that of cTFC [(25.7 ± 6.1) , The difference between the two groups was statistically significant (P <0.05). Conclusions Diver CE aspiration catheter can be used for better efficacy within 3h after acute myocardial infarction.