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目的 观察非典型肺炎患者外周血的CD4~+和CD8~+T淋巴细胞的变化。方法 10例健康人和13例确诊非典型肺炎患者于发病第2周采静脉血,用流式细胞仪检测CD4~+CD8~+T淋巴细胞。结果 与村照组比较,非典型肺炎患者外周血CD4~+,CD8~+T淋巴细胞百分比均有不同程度的降低(P<0.01)。结论 非典型肺炎患者外周血CD4~+、CD8~+T淋巴细胞有不同程度的降低,机体呈异常的免疫反应。
Objective To observe the changes of CD4 ~ + and CD8 ~ + T lymphocytes in peripheral blood of patients with atypical pneumonia. Methods Venous blood was collected from 10 healthy volunteers and 13 patients diagnosed with atypical pneumonia at the second week after the onset of disease. Flow cytometry was used to detect CD4 ~ + CD8 ~ + T lymphocytes. Results Compared with those in the village group, the percentages of CD4 ~ + and CD8 ~ + T lymphocytes in peripheral blood of patients with atypical pneumonia were decreased to some extent (P <0.01). Conclusion The levels of CD4 ~ + and CD8 ~ + T lymphocytes in peripheral blood of patients with atypical pneumonia are reduced to some extent, and the body is abnormally immune.