百两金皂苷A(ardisiacrispin A)是一种三萜皂苷(图1),最早是从植物百两金(Ardisia crispa Thunb)中发现的[1],中药朱砂根(Ardisia crenata Sims)中也有较高含量的分布[2]。有报道称百两金皂苷A能诱导多种肿瘤细胞凋亡,其体外抗肿瘤作用机制与对细胞中caspase-8和caspase-9的活化相关[3-5]。目前,百两金皂苷A的体内实验研究尚未见报道。本实验研究百 Ardisiacrispin A is a triterpene saponin (Figure 1), originally found in Ardisia crispa Thunb [1] and also in Ardisia crenata Sims High content distribution [2]. It has been reported that one hundred two gold saponin A can induce a variety of tumor cell apoptosis in vitro anti-tumor mechanism of action and activation of caspase-8 and caspase-9 cells [3-5]. At present, one hundred two gold saponin A in vivo experimental studies have not been reported. The experimental study hundred