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目的 观察胸椎硬膜外阻滞(TEA)治疗不稳定型心绞痛(UAP)的疗效。方法72例UAP患者随机分为TEA组及单纯药物治疗组(对照组)。TEA组应用英国佳士比9300PCA(患者自控镇痛泵)于胸椎硬膜外注入0.0625%丁哌卡因(布吡卡因)与10μg/kg吗啡混合液,以4ml/h速度注入,连续7~10d。结果TEA组治疗心绞痛起效快,总有效率100%(P<0.01),且能减少心绞痛发作频率、缩短发作持续时间;心电图改善总有效率91.7%(P<0.01);硝酸甘油停减率100%。结论TEA治疗UAP疗效显著、方便、安全。“,”Objective To observe the effectiveness of thoracic epidural anesthesia (TEA) for the treatment of unstableangina pectoris (UPA). Methods 72 UAP patients were randomly divided into two groups: TEA group and control groupwith pure drug therapy. 0. 0625 % of bupivacaine mixed into 10ug/kg of morphine was injected into TEA group at speed of4ml/h for about 710 days through 9300PCA.. Results UAP patients in TEA group responded to the treatment with muchmore effect, and the effective rate was 100 % (P < 0.01), and the UAP frequency and its lasting time were also reducedaccordingly. The total improvement shown in the electrocardiogram was 91.7 % (P< 0.01). Nitroglycerinum was stoppedor reduced (100 % ). Conclusion TEA is a safe, effective and convenient method for the treatment of UAP.