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目的:探讨应用稳心颗粒治疗冠心病心绞痛患者远期的临床效果及安全性分析。方法:将门诊或入院诊断为不稳定性心绞痛的患者160例,随机双盲分为治疗组(86例)和对照组(74例),对照组常规给予ADP受体拮抗剂、β受体阻滞剂、硝酸酯类药物、血管紧张素转换酶抑制剂(ACEI),治疗组在此基础上加用稳心颗粒,9g/次,3次/d,均治疗12个月。分别在治疗6个月、12个月时观察治疗总有效率、血液流变学有关指标分析、血脂变化等项目。结果:治疗组临床症状缓解率、血液流变学指标、血脂分析等情况均优于对照组。结论:步长稳心颗粒联合常规用药长期治疗不稳定性心绞痛临床治疗效果显著。
Objective: To investigate the long-term clinical effect and safety analysis of Wenxin Granule in treating angina pectoris patients with coronary heart disease. Methods: One hundred and sixty patients diagnosed as unstable angina at outpatient or admission stage were randomly divided into treatment group (86 cases) and control group (74 cases). The control group was given ADP receptor antagonist and β receptor block Dextrins, nitrates and angiotensin converting enzyme inhibitor (ACEI) were used in the treatment group. The rats in the treatment group were treated with Wenxinkeli Granules, 9g / time and 3 times / d for 12 months respectively. Respectively in the treatment of 6 months, 12 months to observe the total effective rate of treatment, hemorheology related indicators analysis, changes in blood lipids and other projects. Results: The clinical symptom response rate, hemorheology index, blood lipid analysis and so on in the treatment group were better than those in the control group. Conclusion: The long-term and steady-heart particles combined with conventional treatment of long-term treatment of unstable angina clinical treatment of significant effect.