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用化学药物预防疟疾的安全性和作用一直为公共卫生所关注。世界卫生组织流行病学周刊载文,认为最近报告的6例死亡病例是死于长效磺胺/乙胺嘧啶所致严重皮肤反应,他们因预防恶性疟而服用该药和氯喹。此致命反应进一步说明该预防方案不能令人满意。
The safety and the role of chemical drugs in the prevention of malaria have been of concern to public health. The WHO Epidemiology Weekly article states that the six newly reported deaths were due to severe skin reactions due to long-acting sulfonamide / pyrimethamine, who took the drug and chloroquine for the prevention of falciparum malaria. This deadly response further illustrates that the prevention program is unsatisfactory.