论文部分内容阅读
目的:探讨超声消融治疗对不同部位子宫肌瘤消融率及瘤体大小的影响。方法:选取2014年1月至2015年1月收入我院妇产科的子宫肌瘤患者83例为研究对象,根据肌瘤类型分为浆膜下肌瘤组、黏膜下肌瘤组和肌壁间肌瘤组,采用磁共振成像(MRI)检测患者的肌瘤消融率及瘤体大小变化,采用症状严重程度(SSS)评分表评价患者的临床症状。结果:83例子宫肌瘤患者共111个肌瘤,其中浆膜下肌瘤组38例57个(51.3%),黏膜下肌瘤组29例36个(26.1%),肌壁间肌瘤组16例18个(16.2%)。浆膜下肌瘤组患者的消融率低于黏膜下肌瘤组和肌壁间肌瘤组,但差异无统计学意义(P>0.05)。治疗后6及12个月,黏膜下肌瘤组患者的肌瘤体积缩小率显著高于浆膜下肌瘤组和肌壁间肌瘤组,差异具有统计学意义(P<0.05);而浆膜下肌瘤组和肌壁间肌瘤组比较,差异无统计学意义(P>0.05)。与治疗前比较,治疗后6及12个月3组患者的SSS评分均显著降低,差异具有统计学意义(P<0.05)。3组患者的不良反应比较,差异无统计学意义(P>0.05)。结论:超声消融治疗对浆膜下、黏膜下和肌壁间肌瘤患者具有较好的治疗效果,能够显著改善患者的临床症状,减小肌瘤体积,取得较高的肌瘤消融率,为子宫肌瘤患者提供了新的治疗手段。
Objective: To investigate the effect of ultrasound ablation on uterine fibroids ablation rate and tumor size at different sites. Methods: From January 2014 to January 2015, 83 cases of uterine leiomyoma who were admitted to obstetrics and gynecology department of our hospital from January 2014 to January 2015 were selected and divided into subserosal fibroids group, submucosal fibroids group and muscle wall In myoma group, the patients’ fibroids ablation rate and tumor size change were detected by magnetic resonance imaging (MRI). The symptom severity (SSS) was used to evaluate the clinical symptoms. RESULTS: A total of 111 fibroids were found in 83 cases of myoma of uterus, including 57 (51.3%) in 38 cases of subserosal fibroids, 36 (26.1%) in 29 cases of submucous myoma, 16 cases 18 (16.2%). The subarachnoid fibroids group was lower than the submucosal fibroids group and intramural fibroids group, but the difference was not statistically significant (P> 0.05). At 6 and 12 months after treatment, the fibroids volume shrinkage in submucosal fibroids group was significantly higher than that in subserosal myofibers and myofibrous myoma group (P <0.05) There were no significant differences between the submucous myoma group and the intramural fibroids group (P> 0.05). Compared with those before treatment, the SSS scores of the three groups were significantly decreased at 6 and 12 months after treatment, with statistical significance (P <0.05). There was no significant difference in adverse reactions between the three groups (P> 0.05). Conclusion: Ultrasound ablation has good therapeutic effect on patients with subserosal, submucosal and intramural fibroids, which can significantly improve the clinical symptoms, reduce the volume of fibroids, and achieve a high rate of fibroids ablation Uterine fibroids patients with new treatments.