根治性前列腺切除术(RP)后是否应用睾酮替代治疗(TRT)一直存在争论。许多临床医生都犹豫是否对RP术后患者应用TRT,他们担心雄激素水平的提高会促进残余肿瘤的进展或复发。最近,一些小样本研究表明,RP后应用TRT能提高患者血清睾酮水平,但并没有增加前列腺特异性抗原(PSA)值。KheraM等评估了TRT治疗对RP后性腺机能减退患者血清PSA和睾酮时评的影响,以及病理性Gleason分级对治疗 There has been controversy over the use of testosterone replacement therapy (TRT) after radical prostatectomy (RP). Many clinicians are hesitant to apply TRT to post-RP patients, and they are concerned that the increase in androgen levels will promote the progression or recurrence of residual tumors. Recently, a few small sample studies have shown that the application of TRT after RP increases serum testosterone levels but does not increase the value of prostate-specific antigen (PSA). KheraM et al evaluated the effect of TRT on serum PSA and testosterone assessment in patients with hypogonadal hypogonadal disease after RP as well as pathological Gleason grading versus treatment