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为了观察急性低氧条件下中枢神经系统机能状态的改变,用改进了的方法测定了健康人乘车抵达海拔4700m高原现场前后,和在实验室内吸入低氧混合气体(相当于海拔4500~4700m)前后的“光单纯反应时”。在两种条件下,所得结果基本相同:人体中枢神经系统对急性低氧的反应有明显个体差异,可区别出稳定型、兴奋型和抑制型三类。其中抑制型现场和实验室分别有83%及75%的人出现急性低氧反应,其他两型合并统计,分别有79%及80%的人基本无反应。反应时抑制型的人急性低氧反应的发生率高。反应时测定方法用来评定急性低氧反应出现程度,其结果与症状学评定法相比,在两种条件下,吻合率分别为81%及78%,不吻合率分别为19%及22%,其中假阳性率分别为6%及10%,假阴性率分别为14%及12%。
In order to observe the changes of functional status of central nervous system under acute hypoxic conditions, healthy people were measured by the modified method before and after they arrived at the site of 4700m above sea level and inhaled hypoxia mixed gas (equivalent to 4500 ~ 4700m above sea level ) Before and after the “light simple reaction time.” Under the two conditions, the results are basically the same: the human central nervous system response to acute hypoxia significant individual differences can be distinguished from stable, excitatory and inhibitory type. Among them, 83% and 75% of the patients in the controlled field and laboratory respectively had acute hypoxia response. In the other two types of patients, 79% and 80% of the patients respectively showed no response. The incidence of acute hypoxia in response-inhibitory human is high. The response time measurement was used to assess the occurrence of acute hypoxia. The results were 81% and 78%, respectively, and the rates of mismatch were 19% and 22%, respectively, compared with the symptomology assessment. The false positive rates were 6% and 10% respectively, and the false negative rates were 14% and 12% respectively.