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选择慢性苯中毒者48例，平均年龄42．3±7．8岁，平均接苯工龄16．0±6．4岁；对照组26例，平均年龄42．5±84岁，进行细胞遗传学及脂质过氧化作用的研究。采用培养法观察到本中毒组与对照组相比，染色体畸变率增加，微核率升高，姐妹染色单体交换率升高（均P≤0．01）；脂质过氧化水平测定本中毒组GSH－PX降低（P＜0．05），MDA升高（P＜0．05）。结果表明：苯中毒者细胞遗传学及脂质过氧化水平均发生改变。
Forty-eight patients with chronic benzene poisoning were selected, with an average age of 42.3 ± 7.8 years and a mean of 16.0 ± 6.4 years of benzene treatment. In the control group, 26 patients with an average age of 42.5 ± 84 years were enrolled in this study. Cytogenetics And lipid peroxidation research. Cultured method was used to observe the toxicosis group compared with the control group, the chromosome aberration rate increased, micronucleus rate increased, sister chromatid exchange rate (all P≤0.01); lipid peroxidation level of the poisoning GSH-PX decreased (P <0.05) and MDA increased (P <0.05). The results show that: benzene poisoning cytogenetics and lipid peroxidation levels are changed.