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周细胞又称为壁细胞、Rouget细胞,是构成微血管壁的主要细胞之一。它不仅对血管的成熟、稳定及功能的维持起重要作用,同时也在机体各组织器官的生长发育、创伤修复等生理病理过程中发挥重要作用。周细胞功能的研究主要集中在细胞多能性、血管功能调节、纤维化过程等方面,在泌尿外科学领域主要表现在肾纤维化、肾血流调节、肾小球滤过等,而男科学领域的相关研究较欠缺。本文就周细胞的定位和来源、分布及形态、细胞标志物和功能等进行综述,为男科学领域周细胞的进一步研究指明方向。
Pericytes, also known as parietal cells, Rouget cells, are one of the major cells that make up the microvascular wall. It not only plays an important role in the maintenance of vascular maturation, stability and function, but also plays an important role in the physiological and pathological processes such as the growth and development of various tissues and organs of the body and wound repair. The study of pericyte function mainly focuses on cellular pluripotency, vascular function regulation and fibrosis process. In the field of urology, it is mainly manifested in renal fibrosis, renal blood flow regulation, glomerular filtration, etc., while male science The field of related research is lacking. In this paper, the location and origin, distribution and morphology of pericytes, cell markers and functions were reviewed, pointing out the direction for further research on pericytes in the field of male science.