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1969年冬克山病在黑龙江省尚志县亮河公社九里大队九里屯流行,我们曾给20余名克山病患者,每周口服亚硒酸钠1～2毫克,连续2个月左右,其中没有一人急发。1970年冬我们又在该屯198名居民中试用此药,结果亦无一人急发;当时周围居民的克山病急发率为1.1%(729人中有8例“急发”)。考虑到这些现象可能与服用亚硒酸钠有关,我们于1971年10月至1972年4月又继续在九里屯进行此项现场观察,并将观察范围加以扩大,以期对口服亚硒酸钠预防克山病的效果做出评价。
KBS disease in 1969 in Heilongjiang Province Shangzhi County Lianghe commune Jiu Li Brigade Jiulitun popular, we have given more than 20 patients with Keshan disease, weekly oral sodium selenite 1 ~ 2 mg for about 2 months, of which No one urgent. In the winter of 1970, we tested the drug again among the 198 residents of this village. As a result, no one was in a rush. Kieker’s disease rate among residents in the surrounding areas was 1.1% (8 out of 729 patients were “urgent”). Considering that these phenomena may be related to taking sodium selenite, we continued to conduct this on-site observation at Jiulitun from October 1971 to April 1972 and expanded the scope of observation to evaluate the effectiveness of oral sodium selenite prevention Keshan disease to make the evaluation of the effect.