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目的:观察中西药合用治疗慢性心功能不全的疗效与安全性。方法:82例患者随机分为两组,中西药联合组47例,西药联合组35例。中西药联合组采用三子养亲汤加减,西药联合组采用卡托普利作为对照,两组均联合使用利尿荆和地高辛。观察心功能、心功能参数、血压、心率及安全性指标的变化。结果:中药组显效率40.4％。总有效率89.4％,西药组显效率42.9％,总有效率77.1％;两组LVEF和E/A均有明显提高,中药组比西药组明显;心率和血压均有明显下降,组间无显著差异。两组血、尿常规,肝肾功能均未见异常。结论:中西药联合治疗心功能不全,可能比西药与西药联合疗效要好,而且更安全可靠。
Objective: To observe the curative effect and safety of Chinese and western medicine in treating chronic heart failure. Methods: Eighty-two patients were randomly divided into two groups: 47 cases in combination with Western medicine and 35 cases in western medicine. Combination of Chinese and Western medicine with three sons adopted decoction, Western combined group using captopril as a control, both groups were used in combination with diuretic Jing and digoxin. The changes of cardiac function, cardiac function parameters, blood pressure, heart rate and safety index were observed. Results: Chinese medicine group markedly efficient 40.4%. The total effective rate was 89.4%, the effective rate was 42.9% in the western medicine group and the total effective rate was 77.1%. The LVEF and E / A in both groups were significantly increased, while those in the TCM group were significantly lower than those in the western medicine group difference. Two groups of blood, urine, liver and kidney function were normal. Conclusion: The combination of Chinese and Western medicine in treating cardiac insufficiency may be better than Western medicine and Western medicine, and more safe and reliable.