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目的 探讨倍欣对 2型糖尿病降糖作用的疗效。方法 将单纯饮食控制或加用磺脲类药物治疗不满意的2型糖尿病人 198例 ,随机分为倍欣组 10 0例和二甲双胍组 98例 ,疗程为 8WK。结果与结论 倍欣和二甲双胍对空服血糖均有显著性下降 ,总有效率分别为 86 .0 %、 90 .8% ,但两药降低幅度无统计学意义 P>0 .0 5 ;而倍欣对餐后 2 h血糖的疗效高于二甲双胍 ,总有效率分别为 94 .0 %、 81.6 3% (P<0 .0 1) ;两药均能明显降低 GHb AIc,但倍欣疗效高于二甲双胍 P<0 .0 5 ;两种药物不刺激胰岛素分泌 ,对肝肾功能无影响
Objective To investigate the effect of bexin on type 2 diabetes hypoglycemic effect. Methods A total of 198 patients with type 2 diabetes mellitus who were not satisfied with diet control or sulfonylurea treatment were randomly divided into Beixin group and metformin group, 98 cases were treated with 8WK. RESULTS AND CONCLUSION Bixin and metformin had a significant decrease of blood sugar in patients with oral administration, the total effective rates were 86.0% and 90.8% respectively, but there was no significant difference between the two drugs in decreasing P> 0.05 Yan 2 h postprandial blood glucose higher than the efficacy of metformin, the total effective rate was 94.0%, 81.6 3% (P <0.01); both drugs can significantly reduce the GHb AIc, but times the effect of Xin better than Metformin P <0. 05; two drugs do not stimulate insulin secretion, no effect on liver and kidney function