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目的探讨妊娠期高血压病(妊高征)、胎膜早破等围生因素对新生儿结局的影响。方法选取2011年6月-2013年12月在洛阳市103家医院出生的54 378例新生儿作为回顾性分析对象,根据产妇有无妊娠期高血压病、胎膜早破,对新生儿予以分组比较。结果有妊高征组,出生低体重儿,新生儿畸形、死亡、早产、胎膜早破剖宫产的发生率均明显高于无妊高征组,差异均有统计学意义(P<0.05)。而两组间先天性心脏病的发生率比较差异无显著性(P>0.05)。有胎膜早破组,妊高征、出生低体重儿、早产的发生率均高于无胎膜早破组,新生儿Apgar评分低于对照组,差异均有统计学意义(P均<0.05);新生儿死亡、先天畸形的发生率两组间比较差异无显著性(P>0.05)。结论妊娠期高血压病、胎膜早破等围生因素对于新生儿结局均会产生不同程度的不良影响。
Objective To investigate the effects of perinatal factors such as gestational hypertension (PIH) and premature rupture of membranes on neonatal outcomes. Methods 54 378 newborns born in 103 hospitals in Luoyang from June 2011 to December 2013 were retrospectively analyzed. Neonates were divided into groups according to their pregnancy-induced hypertension and premature rupture of membranes Compare Results The incidence of cesarean section in PIH group, low birth weight infants, neonatal deformity, death, premature rupture of membranes and premature rupture of membranes were significantly higher than those in non-pregnancy induced hypertension group (P <0.05 ). The incidence of congenital heart disease between the two groups showed no significant difference (P> 0.05). The incidence of premature rupture of membranes, pregnancy-induced hypertension, low birth weight infants, the incidence of preterm birth were higher than those without premature rupture of membranes, neonatal Apgar score was lower than the control group, the differences were statistically significant (P <0.05 ); Neonatal deaths, the incidence of congenital malformations between the two groups was no significant difference (P> 0.05). Conclusions Perinatal factors such as hypertensive disorder complicating pregnancy and premature rupture of membranes have adverse effects on neonatal outcome to varying degrees.