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整合素广泛表达于多种细胞表面,在体内生理和病理过程中发挥重要作用。去整合素和整合素受体特异结合而抑制细胞的黏附,在血小板的聚集、肿瘤的侵袭与转移方面研究较多,在眼组织的研究较少。现就二者在病变眼组织中的作用综述如下。1 整合素的结构和生物学功能1 1 整合索的结
Integrins are expressed extensively on a variety of cell surfaces and play an important role in the physiology and pathology of the body. To integrin and integrin receptor-specific binding inhibition of cell adhesion in the platelet aggregation, tumor invasion and metastasis of more research in the eye tissue less. The role of the two in diseased ocular tissues is summarized below. 1 integrin structural and biological functions 1 1 integrated cable knot