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目的:通过观察42例肥胖的糖尿病患者和25例非肥胖的糖尿病患者的代谢状态,了解其代谢紊乱的特点和程度,为改善糖尿病人的代谢状态及血管并发症的防治提供临床依据。结果:肥胖组甘油三酯水平明显高于非肥胖组。血总胆固醇水平两组间无明显差异。可见明显的LDL-c升高和HDL-c降低。血浆胰岛素、血尿酸水平及24小时尿微量白蛋白排泄量肥胖组均有明显增高。两组间比较均有统计学意义。结论:在肥胖的2型糖尿病有明显的代谢紊乱,肥胖越严重,所引起的代谢紊乱越严重。所以对2型糖尿病伴有肥胖的患者应予以重视,对其各种代谢异常进行综合治疗,从而控制和减慢糖尿病血管并发症的发展进程
Objective: To observe the metabolic status of 42 obese diabetic patients and 25 non-obese diabetic patients to understand the characteristics and degree of metabolic disorders, and to provide a clinical basis for the prevention and treatment of diabetic patients with metabolic status and vascular complications. Results: The level of triglyceride in obese group was significantly higher than that in non-obese group. Blood total cholesterol levels no significant difference between the two groups. Significantly elevated LDL-c and decreased HDL-c were seen. Plasma insulin, serum uric acid levels and 24-hour urinary albumin excretion were significantly higher in the obese group. Comparison between the two groups was statistically significant. Conclusion: There are obvious metabolic disorders in obese type 2 diabetes. The more severe the obesity, the more serious the metabolic disorder. Therefore, patients with type 2 diabetes associated with obesity should pay attention to its comprehensive treatment of various metabolic disorders, thereby controlling and slowing the development of diabetic vascular complications