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目的观察雾化吸入普米克令舒治疗慢性阻塞性肺疾病急性加重期(AECOPD)的临床效果。方法将80例AECOPD患者作为研究对象,随机分成2组:A组40例雾化吸入普米克令舒加常规治疗;B组40例给予常规治疗。治疗前后分别进行呼吸困难评分、肺功能、血气分析、血糖、电解质等检测及观察不良反应。结果两组治疗前后呼吸困难评分、肺功能、血气分析等相比差异有统计学意义(P<0.05),而血糖、电解质比较差异无统计学意义(P>0.05)。结论雾化吸入普米克令舒可明显改善AECOPD患者肺功能并迅速缓解临床症状,具有起效快、不良反应少等优点。
Objective To observe the clinical effect of inhalation of pulmicort respules in the treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods Eighty patients with AECOPD were randomly divided into two groups: 40 patients in group A received routine inhalation of pulmicort systolic and 40 patients in group B received conventional therapy. Respiratory dysfunction score, pulmonary function, blood gas analysis, blood glucose, electrolytes and other adverse reactions were observed before and after treatment. Results Before and after treatment, the difference of dyspnea score, pulmonary function and blood gas analysis between the two groups had statistical significance (P <0.05), but there was no significant difference between the two groups in blood glucose and electrolytes (P> 0.05). Conclusion Pulmonic inhalation of Pulmicort respules can significantly improve pulmonary function in patients with AECOPD and quickly relieve clinical symptoms, with fast onset, fewer adverse reactions.