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Cockroaches,commonly found in urban dwellings worldwide,have long been considered vectors of variousinfectious diseases and cockroach allergens are one of the major etiologic risk factors for IgE-mediated allergicrespiratory illness throughout the world.A high prevalence of cockroach hypersensitivity in atopie(20-55%)andasthmatic(49-60%)populations has been documented.Cockroach allergens with molecular weights ranging from 6to 120 kD have been identified by various standard immunochemical techniques.This article covers thecharacteristics of major cockroach allergens that have been purified,sequenced,cloned,and produced asrecombinant proteins.Cellular & Molecular Immunology.2005;2(3):177-180.
Cockroaches, commonly found in urban dwellings worldwide, have long been considered vectors of various non-viral diseases and cockroach allergens are one of the major etiologic risk factors for IgE-mediated allergic respiratory disease throughout the world. A high prevalence of cockroach hypersensitivity in atopie (20-55 %) andasthmatic (49-60%) populations has been documented. Cockroach allergens with molecular weights ranging from 6 to 120 kD have been identified by various standard immunochemical techniques. This article covers the characteristics of major cockroach allergens that have been purified, sequenced, cloned, and produced asrecombinant proteins. Cellular & Molecular Immunology. 2005; 2 (3): 177-180.