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目的 认识肝细胞癌致阻塞性黄疸的临床特点 ,了解本病的发病机理及发病率低、误诊率高的原因 ,提高对本病的早期诊断和疗效。方法 5例均经手术解除胆道梗阻 ,其中 2例行肝动脉插管导向化疗。结果 本组病例的发病率为 5 .2 % ,误诊率占 80 %。经手术解除胆道梗阻后 ,均改善了生活质量 ,且 2例插导管用化疗的患者生存期延长了 5～ 11个月。结论 充分认识此疾病 ,应用恰当的检查技术 ,早期诊断 ,及时手术解除胆道梗阻 ,辅以区域化疗是提高疗效的关键。
Objective To understand the clinical features of obstructive jaundice caused by hepatocellular carcinoma, to understand the pathogenesis of the disease and the reasons for its low incidence and high misdiagnosis rate, and to improve the early diagnosis and efficacy of this disease. Methods 5 cases were treated with biliary obstruction and 2 of them underwent hepatic artery catheter-guided chemotherapy. Results The incidence of this case was 5.2%, and the rate of misdiagnosis accounted for 80%. After surgical relieving biliary obstruction, the quality of life was improved, and the survival of 2 patients with catheter-assisted chemotherapy was prolonged by 5 to 11 months. Conclusion Full understanding of the disease, proper application of diagnostic techniques, early diagnosis, and prompt surgical resection of biliary obstruction, supplemented by regional chemotherapy, are the keys to improved outcomes.