关于铍病的发病机理,已有不少论据,证明铍和活组织的互相作用,涉及到免疫因素的作用。De Nardi、Ordstrand 等(1949)首先报导了患急性铍皮炎患者身体存在对铍的变态反应。两年后,Stener 及 Eisenbud 提出自己的假说,认为以铍化合物作为抗原,可产生一种 On the pathogenesis of beryllium disease, there are many arguments to prove the interaction between beryllium and living tissue, involving the role of immune factors. De Nardi, Ordstrand et al. (1949) first reported the presence of beryllium in the body of patients suffering from acute beryllium dermatitis. Two years later, Stener and Eisenbud put forward their own hypothesis that beryllium compounds as antigens, can produce a