瘢痕妊娠患者预防性子宫动脉栓塞术中侧支血管残留与刮宫术中出血的关系

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目的:探讨剖宫产术后瘢痕妊娠患者行子宫动脉栓塞术后,残余侧支血管与刮宫术中出血风险的关系。方法:回顾性收集2012年1月至2019年6月山东省立医院499例瘢痕妊娠患者资料,均于刮宫术前行预防性子宫动脉栓塞术。术中发现子宫侧支血管的患者尽可能栓塞侧支血管。根据栓塞结束时子宫体中下部残余染色浓度由低到高分为A、B、C 3类,A类无染色或轻度染色,B类中度染色,C类明显染色。记录患者刮宫术中出血量,计算3类患者刮宫术中小量出血(5 00 ml)发生率,并采用χ2检验或Fisher确切概率法分别与对照组(无子宫侧支血管患者)比较。结果:53例患者存在侧支血管,栓塞后A、B、C类患者分别为25、15、13例,行侧支血管栓塞36例。B、C类患者刮宫术中小量出血发生率[60.0%(9/15)和46.2%(6/13)]低于对照组(87.9%,392/446),差异有统计学意义(χ2=9.972,n P=0.002;χ2=19.090,n P<0.001);C类患者大出血发生率(23.1%,3/13)明显高于对照组(2.2%,9/446),差异有统计学意义(χ2=14.480,n P=0.001)。n 结论:存在子宫侧支血管的瘢痕妊娠患者,栓塞侧支血管可减少刮宫术中出血量,子宫体中下部残余染色对预测刮宫术中大出血风险有意义。“,”Objective:To explore the relationship between residual collateral vessels in uterine arterial embolization (UAE) and the risk of bleeding during the operation of curettage for cesarean scar pregnancy.Methods:A total of 499 patients who underwent preventive UAE before curettage for scar pregnancy in Shandong Provincial Hospital from January 2012 to June 2019 were included. Clinical data of the patients were retrospectively collected and analyzed. In patients with uterine collateral circulation, collateral vessels were embolized as much as possible. Angiography was performed after UAE. All the cases were divided into 3 grades according to residual staining in middle and lower part of corpus uteri as follows, grade A: no or mild staining, grade B: moderate staining, grade C: intense staining. Blood loss of the patients during curettage was recorded, and the incidence rate of minor hemorrhage (500 ml) of the 3 grades were calculated respectively. The results of three grades groups were compared with those of control group (patients without collateral circulation) by using Chi-square test or Fischer exact probability.Results:According to angiogram acquired after UAE, collateral vessels were found in 53 patients, with 25 cases in grade A group, 15 cases in grade B group, and 13 cases in grade C group, respectively. Thirty-six patients underwent transcatheter embolization of collateral vessels. The incidence rate of minor hemorrhage in type B and C [60.0% (9/15), 46.2% (6/13)] was lower than that in control group (87.9%, 392/446), with significant difference found (χ2=9.972, n P=0.002, χ2=19.090, n P<0.001). Significant difference was found in the incidence rate of massive haemorrhage between group C (23.1%, 3/13) and control group (2.2%, 9/446) (χ2=14.480,n P=0.001).n Conclusion:As for cesarean scar pregnancy cases with uterine collateral vessels, embolization of collateral vessels may reduce the amounts of bleeding during curettage. Residual staining of middle and lower part of corpus uteri may be helpful in predicting the risk of massive haemorrhage during curettage.
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