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免疫系统的基本功能是认识自己和排斥异已。变态反应是免疫反应的一个类型。由于免疫功能的缺陷,导致某些免疫反应过强,发生组织损伤。引起变态反应的抗原通常是无害的,但机体却以过分剧烈的反应企图清除它,结果反而引起组织损伤。变态反应的分型,目前普遍承认的是4型分型法(表1)(图1)。Ⅰ型变态反应又称速发型变态反应,它的发生分两个阶段,致敏和激发:在致敏阶段,抗原刺激产生的 IgE 结合于肥大细胞表面,使之致敏,在激发阶段,被致敏的肥大细胞再次暴露于同一抗原就会导
The basic function of the immune system is to recognize oneself and exclude oneself. Allergies are a type of immune response. Due to defects in immune function, some of the immune response is too strong, tissue damage occurs. The antigen that causes the allergic reaction is usually harmless, but the body tries to clear it with an overly violent reaction, which in turn can cause tissue damage. The type of allergy, the current general recognition of type 4 typing (Table 1) (Figure 1). Type I allergy, also known as rapid-onset allergic reaction, its occurrence in two stages, sensitization and challenge: In the sensitization phase, IgE produced by antigen stimulation binds to the surface of mast cells to sensitize them during the provocation phase Sensitive mast cells re-exposure to the same antigen will guide