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昆明种小鼠预先接受50mGyX射线照射或不同浓度小剂量丝裂霉素C注射,然后再分别接受不同浓度大剂量丝裂霉素C或1.5GyX射线辐射处理。其预先处理组骨髓细胞和生殖细胞染色体畸变率均明显低于单纯处理组,表明丝裂霉素C和X射线在小鼠整体内可诱发交叉适应性反应;且适应性反应程度与适应性处理和攻击性处理的丝裂霉素C浓度呈负相关。
Kunming mice were pre-treated with 50mGy X-ray or different doses of low dose mitomycin C injection, and then were treated with different concentrations of high doses of mitomycin C or 1.5Gy X-ray irradiation. The pretreatment group bone marrow cells and germ cell chromosome aberration rates were significantly lower than the simple treatment group, indicating that mitomycin C and X-ray can induce cross-adaptation in mice as a whole; and adaptive response and adaptive treatment And negatively correlated with the concentration of mitomycin C for aggressive treatment.