论文部分内容阅读
目的探讨饮食、运动早期干预对青年非酒精性脂肪肝(nonalcoholic fatty liuer disedse,NAFLD)的疗效。方法选择180例青年NAFLD患者,随机分成饮食干预组、运动干预组、饮食加运动联合干预组,每组60例,进行健康知识教育后,干预6个月,分别监测干预前后各组血清总胆固醇(total cholesterol,TC)、三酰甘油(triglyceride,TG)、丙氨酸转氨酶(alanine aminotransferase,ALT)及胰岛素敏感指数(insulin sensitivity index,ISI)、体质量指数(body mass index,BMI),并观察干预前后肝脏超声声像图变化。结果 3组干预后TG、TC、ALT、ISI、BMI均较干预前明显改善,差异有统计学意义(P<0.01);饮食加运动联合干预组干预后TG、TC、ALT、BMI明显低于饮食干预组、运动干预组(P<0.01),ISI明显高于饮食干预组、运动干预组(P<0.01);饮食加运动联合干预组超声声像图改善率98.3%,临床有效率96.7%,均明显优于饮食干预组和运动干预组,差异有统计学意义(P<0.01)。结论饮食、运动及联合早期干预,对青年NAFLD患者疗效显著。
Objective To investigate the effect of diet, exercise early intervention on young nonalcoholic fatty liuer disedse (NAFLD). Methods 180 cases of young NAFLD patients were randomly divided into dietary intervention group, exercise intervention group, diet plus exercise combined intervention group, 60 cases in each group, after health education, intervention for 6 months, respectively, before and after intervention in the monitoring of serum total cholesterol total cholesterol (TC), triglyceride (TG), alanine aminotransferase (ALT) and insulin sensitivity index (ISI), body mass index (BMI) Changes of liver ultrasonography before and after intervention were observed. Results The levels of TG, TC, ALT, ISI and BMI in the three groups after intervention were significantly improved compared with those before intervention (P <0.01). The levels of TG, TC, ALT and BMI in the intervention group were significantly lower than those in the intervention group Diet intervention group and exercise intervention group (P <0.01), ISI was significantly higher than dietary intervention group and exercise intervention group (P <0.01). The improvement rate of ultrasound echocardiography was 98.3% in diet plus exercise intervention group, and the clinical effective rate was 96.7% , Were significantly better than the diet intervention group and exercise intervention group, the difference was statistically significant (P <0.01). Conclusion Diet, exercise and combined early intervention have significant effects on young NAFLD patients.