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目的观察中西医结合治疗青春期寻常型痤疮的临床疗效。方法青春期寻常型痤疮共126例,随机分为中西医结合组(G1:32例)、中药组(G2:31例)、西药组(G3:33例)和外用组(G4:30例),分别采用中西结合治疗、中药治疗、西医治疗及单纯外用治疗。疗程6周,并分别在第2、4、6周进行疗效比较。结果完成治疗和观察123例。治疗2周,G1有效率为56.3%,优于其它组(P=0.003<0.01);4周,G1痊愈率为50.0%,有效率为84.4%,优于其它组(P<0.05);6周,G1痊愈率为90.6%,有效率为96.9%,优于G4(P<0.01),与其它2组无差别;治疗2周及4周后,G1的皮脂溢出控制效果优于其它组(P<0.05);治疗6周后,G4的皮脂溢出控制效果差于其它组(P<0.05),其它3组无差别(P>0.05)。结论中西医结合治疗青春期寻常型痤疮的起效时间快,临床疗效确切,不增加药物不良反应;中西药结合治疗有协同作用。
Objective To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of acne vulgaris. Methods A total of 126 cases of acne vulgaris were randomly divided into three groups: G1 (32 cases), G2 (31 cases), Western medicine group (G3: 33 cases) and external medicine group (G4: 30 cases) Using Chinese and Western treatment, Chinese medicine treatment, Western medicine treatment and simple external treatment. The course of treatment was 6 weeks and the curative effects were compared at the 2nd, 4th, 6th week respectively. Results The completion of treatment and observation of 123 cases. After 2 weeks of treatment, the effective rate of G1 was 56.3%, which was better than other groups (P = 0.003 <0.01). After 4 weeks, the cure rate of G1 was 50.0% and the effective rate was 84.4% G1, the cure rate of G1 was 90.6%, the effective rate was 96.9%, better than G4 (P <0.01), no difference with the other two groups; after 2 and 4 weeks of treatment, the control effect of G1 on seborrhea was better than other groups P <0.05). After 6 weeks of treatment, the control effect of G4 on seborrhea was worse than that of other groups (P <0.05), but there was no difference in the other three groups (P> 0.05). Conclusion The combination of traditional Chinese and western medicine treatment of adolescent acne vulgaris rapid onset time, the exact clinical efficacy, does not increase the adverse drug reactions; Chinese and Western medicine have a synergistic effect.