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目的:测定膀胱癌患者血清中谷胱甘肽S-转移酶(GST)活性,观察该酶在膀胱癌中的作用。方法:化学比色法对54例膀胱癌患者行GST测定。结果:膀胱癌患者血清SGT平均值较对照组明显升高,膀胱癌患者术后CST降低,与对照组无显著性差异;GST含量在膀胱癌分级分期之间无显著性差异。结论:GST与膀胱癌的发生及发展有关,与膀胱癌恶性度的关系有待于进一步探讨。
Objective: To determine the activity of glutathione S-transferase (GST) in serum of bladder cancer patients and observe the role of this enzyme in bladder cancer. Methods: GST determination was performed on 54 bladder cancer patients by chemical colorimetry. Results: The average serum SGT level of bladder cancer patients was significantly higher than that of the control group. The postoperative CST of bladder cancer patients was not significantly different from that of the control group. There was no significant difference in the GST level among the stages of bladder cancer. Conclusion: GST is associated with the occurrence and development of bladder cancer and its relationship with the malignancy of bladder cancer needs to be further explored.