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目的 观察尼莫通在急性脑出血中的治疗价值。方法 将 84例经头颅 CT证实为基底节脑出血的病人随机分成治疗组和对照组 ,两组均给予降颅压、营养脑细胞及止血降压等常规治疗 ,治疗组同时加用尼莫通 5 0 ml(10 mg)静脉滴注 ,每天 1次 ,共用 10～ 14天 ,治疗前后比较两组病人的颅内血肿、血肿周围水肿带面积及神经功能缺损评分的改变。结果 尼莫通治疗组较对照组血肿周围水肿带面积明显缩小 (P <0 .0 5 ) ,神经功能缺损评分明显改善 (P <0 .0 1) ,血肿体积则改变不显著。结论 在脑出血急性期应用尼莫通治疗可明显改善其病情及预后。
Objective To observe the therapeutic value of nimotop in acute cerebral hemorrhage. Methods Eighty-four patients with cerebral hemorrhage confirmed by skull CT were randomly divided into treatment group and control group. The patients in both groups were given conventional therapy such as intracranial pressure reduction, nutritional brain cells and hemostasis and blood pressure reduction. The patients in treatment group were given nimotone 50 ml (10 mg) intravenously once a day for 10 to 14 days. The changes of intracranial hematoma, the area of edema around the hematoma and the score of neurological deficits were compared before and after treatment. Results Compared with the control group, the area of edema in the nimotop group was significantly reduced (P <0.05), the score of neurological deficit was significantly improved (P <0.01), and the volume of hematoma was not changed significantly. Conclusion The application of nimotop in the acute stage of cerebral hemorrhage can obviously improve its condition and prognosis.