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牛膝多糖（ＡＢＰ）是从传统中药牛膝根中分离得到的一有效成分。ＡＢＰｉｐ５０ｍｇ·ｋｇ－１×５ｄ能明显提高血清总ＩｇＧ及特异性抗体溶血素的含量，并增加脾脏ＰＦＣ数；还能对抗环孢霉素Ａ引起的ＰＦＣ及ＩｇＧ的下降。ＡＢＰ０．２～０．８ｇ·Ｌ－１体外能刺激小鼠脾细胞增殖，也能增强ＬＰＳ诱导的Ｂ淋巴细胞增殖。上述结果表明，ＡＢＰ能增强小鼠的体液免疫功能。
Achyranthes polysaccharide (ABP) is an active ingredient isolated from the traditional Chinese medicine Achyranthes bidentata roots. ABPip50mg · kg-1 × 5d can significantly increase the serum total IgG and specific antibody hemolysin, and increase the number of PFC spleen; but also against cyclosporin A caused PFC and IgG decreased. ABP0.2 ~ 0.8g · L-1 could stimulate the proliferation of mouse spleen cells in vitro and also enhance LPS-induced B lymphocyte proliferation. The above results show that ABP can enhance humoral immune function in mice.