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目的:对参葛降脂浓缩丸进行提取工艺研究。方法:采用正交实验设计以葛根素、人参皂苷Rg1、三七皂苷R1含量之和为乙醇回流提取评价指标,以水蛭的抗凝活性为乙醇渗漉提取评价指标,对提取工艺进行优化。结果:经筛选乙醇回流提取工艺为以8倍量体积的75%乙醇,回流提取2次,每次3h,渗漉提取工艺为8倍量75%乙醇,浸泡24h,渗漉速度20ml/min·kg为最佳工艺参数。结论:该工艺设计合理、可行。
Objective: To study the extraction technology of Shengge Jiangzhi concentrated pills. Methods: Orthogonal experimental design with puerarin, ginsenoside Rg1, notoginsenoside R1 content of ethanol reflux extraction evaluation index, leech anticoagulant activity of ethanol percolation extraction evaluation index, the extraction process optimization. Results: The sieved ethanol reflux extraction process was 8 times the volume of 75% ethanol, reflux extraction 2 times, each time 3h, percolation extraction process for 8 times the amount of 75% ethanol, soaking 24h, percolation rate 20ml / min kg for the best process parameters. Conclusion: The process design is reasonable and feasible.