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目的 :观察口服米索前列醇对预防产后出血的效果。方法 :对 10 0例具有产后出血高危因素的病例随机分为米索前列醇组 (实验组 )和催产素组 (对照组 )。实验组于胎儿娩出以后立即肌肉注射催产素 10 u ,同时口服米索前列醇0 .4mg,对照组于胎儿娩出后立即肌肉注射催产素 10 u。比较两者的效果及副作用。结果 :实验组第三产程明显短于对照组 (P<0 .0 1) ,产后 2 h出血量明显少于对照组 (P<0 .0 1) ,用药前后对血压影响小 (P>0 .0 5 )。结论 :口服米索前列醇能有效预防产后出血 ,对血压影响小 ,尤其适用于高危孕产妇。
Objective: To observe the effect of oral misoprostol on prevention of postpartum hemorrhage. Methods: One hundred and ten patients with high risk of postpartum hemorrhage were randomly divided into misoprostol group (experimental group) and oxytocin group (control group). In the experimental group, oxytocin 10 u was injected intramuscularly immediately after the fetus was delivered, and 0.4 mg of misoprostol was orally administered. In the control group, oxytocin 10 μ was injected intramuscularly immediately after the fetus was delivered. Compare the two effects and side effects. Results: The third stage of labor in the experimental group was significantly shorter than that in the control group (P0.01), and the amount of bleeding 2 h postpartum was significantly less than that of the control group (P0.01) .0 5). Conclusion: Oral misoprostol can effectively prevent postpartum hemorrhage and has little effect on blood pressure, especially for high-risk pregnant women.